Complete Curriculum Vitae (pdf)

EDUCATION

University of Washington, Seattle WA Ph.D. 2001 Molecular Virology

Washington University, St. Louis MO B.A. 1995 Biochemistry

RESEARCH INTERESTS

My long-standing interest is to understand how to prevent human diseases caused by infectious agents. These interests are exemplified by my doctoral work studying the molecular patterns of HIV-1 transmission in human populations and by my post-doctoral work studying the molecular mechanisms underlying Legionella susceptibility in mice. My current focus is on the emerging human pathogen that causes severe acute respiratory syndrome, SARS-CoV. I am developing a rapid diagnostic tool to quickly identify SARS-CoV in biological samples, a key step in stemming future outbreaks like the one that occurred in Spring 2003. As SARS-CoV is one of many pathogens that reside in oral cavities, some of which may be unknown, this project will be expanded to include other pathogens, which may be of use in identification of unknown disease-causing microorganisms.

CURRENT PROJECTS

Detection of Emerging Microbes

SELECTED PUBLICATIONS

Sagar, M., E. Kirkegaard, E. M. Long, C. Celum, S. Buchbinder, E. S. Daar, J. Overbaugh. HIV-1 diversity at the time of infection is not restricted to certain risk groups or specific HIV-1 subtypes. Submitted.

Wright, E. K., S. A. Goodart, J. D. Growney, V. Hadinoto, M. G. Endrizzi, E. M. Long, K. Sadigh, A. L. Abney, I. Bernstein-Hanley, W. F. Dietrich. Naip 5 Affects Host Susceptibility to the Intracellular Pathogen Legionella pneumophila. Curr. Biol., 13:27-36, January 2003.

Long, E. M., S. M. J. Rainwater, L. Lavreys, K. Mandaliya, and J. Overbaugh. HIV-1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus. AIDS Res Hum Retrovirus, 18:567-76 May 2002.

Campbell, A. M, A. J. Coble, L. D. Cohen, T. H. ChÕng, K. M. Russo, E. M. Long, E. V. Armbrust. Identification and DNA sequence of a new H+-ATPase in the unicellular green alga Chlamydomonas reinhardtii (Chlorophyceae). J. Phycology, 37 (4): 536-542, August 2001.

Long, E. M., H. L. Martin, Jr., J. K. Kreiss, S. Jackson, L. Lavreys, D. J. Jackson, J. Rakwar, K. Mandaliya, and J. Overbaugh. Gender differences in HIV-1 diversity at time of infection. Nat. Med., 6: 71-75, January 2000.

Overbaugh, J., J. Kreiss, M. Poss, P. Lewis, S. Mostad, G. John, R. Nduati, D. Mbori-Ngacha, H. Martin, Jr., B. Richardson, S. Jackson, J. Neilson, E. M. Long, D. DeVange, M. Welch, J. Rakwar, D. Jackson, B. Chohan, L. Lavreys, K. Mandaliya, J. Nhinya-Achola, and J. Bwayo. Studies of HIV-1 Mucosal Viral Shedding and Transmission in Kenya. J. Infect. Dis. 179: S401-S404, May, 1999

Rudensey, L. M., J. T. Kimata, E. M. Long, B. Chackerian, and J. Overbaugh. Changes in the extracellular envelope glycoprotein of variants that evolve during the course of simian immunodeficiency virus SIVMne infection affect neutralizing antibody recognition, syncytia formation and macrophage tropism, but not replication, cytopathicity or CCR-5 coreceptor recognition. J. Virol, 72: 209-217, January 1998.

Chackerian, B, E. M. Long, P. A. Luciw, and J. Overbaugh. Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection. J. Virol, 71: 3932-39, May 1997.